{"id":4111,"date":"2025-10-13T09:58:53","date_gmt":"2025-10-13T09:58:53","guid":{"rendered":"https:\/\/naripcheruthuruthy.ccras.res.in\/?page_id=4111"},"modified":"2026-02-20T10:53:30","modified_gmt":"2026-02-20T10:53:30","slug":"drug-standardisation-research","status":"publish","type":"page","link":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/drug-standardisation-research\/","title":{"rendered":"\u0914\u0937\u0927\u093f \u092e\u093e\u0928\u0915\u0940\u0915\u0930\u0923 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928"},"content":{"rendered":"
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\u0914\u0937\u0927\u093f \u092e\u093e\u0928\u0915\u0940\u0915\u0930\u0923 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928<\/u><\/strong><\/p>

Since 2011<\/strong>, the Drug Standardization Unit has been actively engaged in:<\/p>

  • Standardization of Single Drugs<\/strong> (various plant parts such as roots, leaves, stems, and rhizomes).<\/li>
  • Physico-chemical Evaluation<\/strong> of Finished Formulations (Churna, Taila, Ghrita, Capsules, Tablets<\/em>).<\/li>
  • Chromatographic Fingerprinting<\/strong> (TLC\/HPTLC) and marker-based profiling for quality assurance.<\/li>
  • Development of Standard Operating Procedures (SOPs)<\/strong> \u090f\u0935\u0902 Shelf-life Studies<\/strong> for Ayurvedic formulations.<\/li>
  • Phytochemical isolation and characterization<\/strong> of active marker compounds from medicinal plants.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    Major Accomplishments and Projects<\/u><\/strong><\/p>

    • Initiated standardization work on Amalakyadi Churna, Balacaturbhadrika Churna, Rasna Saptakam, and Jwarahara Churna<\/strong> (2011\u20132012).<\/li>
    • Analyzed 176 samples of 53 single drugs<\/strong> \u090f\u0935\u0902 48 samples of 14 formulations<\/strong> (2012\u20132013).<\/li>
    • \u0938\u0902\u092a\u0942\u0930\u094d\u0923 physico-chemical analysis and API standardization<\/strong> of Neem Oil<\/em> \u090f\u0935\u0902 Nimbatiktam powder\/capsule<\/em>.<\/li>
    • Developed and prepared Nimbatiktam 200 mg Capsules<\/strong> under the CCRAS Project (2013\u20132019), supplying 3,000 capsules<\/strong> to peripheral institutes and 6,000 capsules<\/strong> to headquarters.<\/li>
    • Between 2020\u20132025<\/strong>, analyzed over 1,500 samples<\/strong> covering 30 formulations<\/strong> \u090f\u0935\u0902 Ayush\/herbal drugs<\/strong> for selected quality parameters.<\/li>
    • Conducted isolation of marker compounds<\/strong> such as Curcumin, Embelin, Asiaticoside,<\/em> \u090f\u0935\u0902 Arjunolic Acid<\/em> from Curcuma longa, Embelia ribes, Centella asiatica,<\/em> \u090f\u0935\u0902 Terminalia arjuna<\/em>, respectively.<\/li>
    • Maintains a Herbarium Repository<\/strong> of authenticated medicinal plant specimens for research and reference.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      Ongoing IMR and Collaborative Projects<\/u><\/strong><\/p>

      1. QC Analysis, Marker Estimation, and Shelf-Life Studies<\/strong> of Ayush M3<\/em> \u090f\u0935\u0902 Ayush SS Granules<\/em>.<\/li>
      2. QC analysis and Estimation of Markers <\/strong>of Jwarahara Kwatha Choorna (JKC)<\/em> for fever management.<\/li>
      3. Development of SOP and Marker Estimation<\/strong> in Tryushnadi Guggulu<\/em> \u2013 a classical Ayurvedic formulation.<\/li>
      4. Development of Quality Control Protocols<\/strong> for medicated oils: Murivenna, Durvadikera, Bhringamalakadi Kerataila<\/em>.<\/li>
      5. SOP Validation and Shelf-Life Study<\/strong> of MML Taila<\/em>.<\/li>
      6. Evaluation of Brahmi Ghrita<\/strong> in in-vitro<\/em> \u090f\u0935\u0902 in-vivo<\/em> models for Alzheimer\u2019s disease.<\/li><\/ol>

        Pharmaceutical Development and Characterization<\/strong> of Karuthamarmani Gutika<\/em> \u090f\u0935\u0902 Shirostodadi Gutika\/Tablets<\/em>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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        Key Achievements<\/u><\/strong><\/p>

        • Developed and standardized Nimbatiktam 200 mg Capsule<\/strong> formulation.<\/li>
        • Submitted CTD Monograph on Piper longum<\/em><\/strong> to CCRAS.<\/li>
        • \u0938\u0902\u092a\u0942\u0930\u094d\u0923 standardization of Ayurvedic oils, powders, and single drugs<\/strong> for pharmacognostic and analytical profiling.<\/li>
        • Isolated and characterized key bioactive marker compounds<\/strong> from medicinal plants under IMR projects.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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          Completed \u00a0Drug Standardization Research
          <\/strong><\/p>

          S.No.<\/p><\/td>

          Project Name<\/p><\/td><\/tr>

          1.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/p><\/td>

          Isolation of maker compounds of some selected medicinal plants<\/p><\/td><\/tr>

          2.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/p><\/td>

          Preparation of Nimbatiktakam Capsules<\/p><\/td><\/tr>

          3.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/p><\/td>

          QC Analysis and Estimation of\u00a0 Markers in polyherbal formulation \u2018Jwarahara Kwatha Choornam (JKC)\u2019 for the effective treatment of fever<\/p><\/td><\/tr>

          4.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/p><\/td>

          QC Analysis, Estimation of\u00a0 Markers\/PRS & shelf life studies of AYUSH M3 and AYUSH SS Granules<\/p><\/td><\/tr>

          5.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/p><\/td>

          Development of SoP, Estimation of maker compounds in polyherbal formulation: Tryushnadi Guggulu-A Classical Ayurvedic formulation<\/p><\/td><\/tr>

          6.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/p><\/td>

          Development of quality Control protocols, identification, and estimation of\u00a0 major bioactive \u00a0constituents of Ayurvedic Medicated oils \u2018Murivenna\u2019, \u2018Durvadi kera\u2019,Bhringamalakadi \u00a0Kerataila<\/p><\/td><\/tr>

          7.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/p><\/td>

          Pharmaceutical Standardization of Polyherbal Formulations MML Taila with Shelf-Life Study.<\/p><\/td><\/tr>

          8.<\/p><\/td>

          Pharmaceutical development and characterization of karuthamarmani gutika\/tablet\/shirastod adi gutika\/ table<\/p><\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

          Drug Standardisation Research Since 2011, the Drug Standardization Unit has been actively engaged in: Standardization of Single Drugs (various plant parts such as roots, leaves, stems, and rhizomes). Physico-chemical Evaluation of Finished Formulations (Churna, Taila, Ghrita, Capsules, Tablets). Chromatographic Fingerprinting<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4111","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/pages\/4111","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/comments?post=4111"}],"version-history":[{"count":7,"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/pages\/4111\/revisions"}],"predecessor-version":[{"id":4233,"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/pages\/4111\/revisions\/4233"}],"wp:attachment":[{"href":"https:\/\/naripcheruthuruthy.ccras.res.in\/hi\/wp-json\/wp\/v2\/media?parent=4111"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}