दवा मानकीकरण अनुसंधान
Since 2011, the Drug Standardization Unit has been actively engaged in:
- Standardization of Single Drugs (various plant parts such as roots, leaves, stems, and rhizomes).
- Physico-chemical Evaluation of Finished Formulations (Churna, Taila, Ghrita, Capsules, Tablets).
- Chromatographic Fingerprinting (TLC/HPTLC) and marker-based profiling for quality assurance.
- Development of Standard Operating Procedures (SOPs) और Shelf-life Studies for Ayurvedic formulations.
- Phytochemical isolation and characterization of active marker compounds from medicinal plants.
Major Accomplishments and Projects
- Initiated standardization work on Amalakyadi Churna, Balacaturbhadrika Churna, Rasna Saptakam, and Jwarahara Churna (2011–2012).
- Analyzed 176 samples of 53 single drugs और 48 samples of 14 formulations (2012–2013).
- Completed physico-chemical analysis and API standardization of Neem Oil और Nimbatiktam powder/capsule.
- Developed and prepared Nimbatiktam 200 mg Capsules under the CCRAS Project (2013–2019), supplying 3,000 capsules to peripheral institutes and 6,000 capsules to headquarters.
- Between 2020–2025, analyzed over 1,500 samples covering 30 formulations और Ayush/herbal drugs for selected quality parameters.
- Conducted isolation of marker compounds such as Curcumin, Embelin, Asiaticoside, और Arjunolic Acid from Curcuma longa, Embelia ribes, Centella asiatica, और Terminalia arjuna, respectively.
- Maintains a Herbarium Repository of authenticated medicinal plant specimens for research and reference.
Ongoing IMR and Collaborative Projects
- QC Analysis, Marker Estimation, and Shelf-Life Studies of Ayush M3 और Ayush SS Granules.
- QC analysis and Estimation of Markers of Jwarahara Kwatha Choorna (JKC) for fever management.
- Development of SOP and Marker Estimation in Tryushnadi Guggulu – a classical Ayurvedic formulation.
- Development of Quality Control Protocols for medicated oils: Murivenna, Durvadikera, Bhringamalakadi Kerataila.
- SOP Validation and Shelf-Life Study of MML Taila.
- Evaluation of Brahmi Ghrita in in-vitro और in-vivo models for Alzheimer’s disease.
- Pharmaceutical Development and Characterization of Karuthamarmani Gutika और Shirostodadi Gutika/Tablets.
Key Achievements
- Developed and standardized Nimbatiktam 200 mg Capsule formulation.
- Submitted CTD Monograph on Piper longum to CCRAS.
- Completed standardization of Ayurvedic oils, powders, and single drugs for pharmacognostic and analytical profiling.
- Isolated and characterized key bioactive marker compounds from medicinal plants under IMR projects.